Please use this identifier to cite or link to this item: http://repo.lib.jfn.ac.lk/ujrr/handle/123456789/9625
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dc.contributor.authorThuvaragan, S.-
dc.contributor.authorJeyasinghe, H.M.P.M.-
dc.contributor.authorMurugananthan, A.-
dc.date.accessioned2023-08-14T04:37:24Z-
dc.date.available2023-08-14T04:37:24Z-
dc.date.issued2021-
dc.identifier.citationThuvaragan.S, H.M.P.M. Jeyasinghe, Murugananthan. A (2021) Comparative Evaluation of in - vitro Anthelmintic Activity of Sap, Fruit bulb, and Root of Borassus flabellifer. Proceeding of the Public Health and Well-being Conference, Vol. 1, 2021, pp. 43-50. https://doi.org/10.32789/publichealth.2021.1011en_US
dc.identifier.urihttp://repo.lib.jfn.ac.lk/ujrr/handle/123456789/9625-
dc.description.abstractHelminth infections are major health problems, especially in developing countries with warm and humid environments. Limited synthetic drugs are available for treating helminth infections, and some of them showed resistance to helminths. Phytoconstituents can be used to develop cheap and effective anthelminthic drugs. Borassus flabellifer has been used in traditional medicine, in addition to consuming as food. This study was designed to evaluate the comparative in vitro anthelmintic activities of aqueous and methanol extracts of root, fruit pulp, and sap of Borassus flabellifer using two different concentrations (50 and 100 mg/mL). Adult earthworms, Eisenia fetida was used to evaluate the in-vitro anthelmintic activity. In-vitro anthelmintic activity was evaluated by determining times of paralysis and the death of worms. The anthelminthic activity of extracts was compared with mebendazole, and earthworm saline was used as a control. ANOVA followed by Dunnett’s multiple comparison test was used to compare the activities of extracts with mebendazole. All extracts showed concentrations dependent activity. All extracts except aqueous extract of roots of Borassus flabellifer showed statistically significant in-vitro anthelminthic activity. Further studies are needed to isolate and evaluate the active components from the extracts of Borassus flabellifer.en_US
dc.language.isoenen_US
dc.publisherPublic Health and Well-beingen_US
dc.subjectBorassus flabelliferen_US
dc.subjectSapen_US
dc.subjectRooten_US
dc.subjectFruit bulben_US
dc.subjectExtractsen_US
dc.titleComparative Evaluation of in - vitro Anthelmintic Activity of Sap, Fruit bulb, and Root of Borassus flabelliferen_US
dc.typeArticleen_US
dc.identifier.doihttps:/doi.org/10.32789/publichealth.2021.1011en_US
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